Hydranencephaly after Maternal Butane-gas Intoxication during Pregnancy . Hydranence’phalie apr.?s intoxication maternelle par le gaz butane durant la. Autoerotic Accident by Inhalation of Propane-Butane Gas Mixture Toxicologic investigations revealed an intoxication with propane and butane .. kan ve doku örneklerinde gaz komponentlerinin analizinin yap›labilmesi tan›. Butane is a colourless and flammable gas with a gasoline-like or natural gas This paper discusses the medico-legal approach for this type of intoxication.

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Propane and isobutane were also detected. Cardiac status improved during hospitalization, but brain functions remained disturbed Bauman et al. The Royal Society of Chemistry.

However, the LC 01 can be calculated because the mean is known and the standard deviation of the underlying lognormal distribution can be derived from these data. Some data are available on cardiac effects in dogs, but they are insufficient for setting AEGL values.

Mortality from butane in mice and rats is preceded by CNS effects. The relative anesthetic activity of the butanes and pentanes; pp. In Virginia, 39 cases of people who likely died as a direct consequence abusing an inhalant were found between and The Bulletin of Legal Medicine requires the author as the rights holder to sign and submit the journal’s agreement form prior to acceptance.

American Journal of Applied Sciences. Psychosocial supports should be provided by key workers or counsellors. Les auteurs pensent que la malformation Ctait d8e a une anoxie intra-utbrine survenant durant le dkveloppement foetal du cerveau. A narcotic, asphyxiant, or flammable hazard? Raman Spectroscopy Study of n -Pentane and n -Butane”. Because it is easily accessible, butane is often used in inhalant abuse. Elsevier, New York, Groups of mice sex and strain not specified were exposed to butane at concentrations of , , , orppm; 6 mice were tested at the lowest concentration and 10 mice at each of the higher concentrations Stoughton and Lamson The term may refer to either of two structural isomersn -butane or isobutane also called “methylpropane”or to a mixture of these isomers.


A CT head scan on the day following admission to the hospital was normal. The results of the key study in mice are comparable with the results from a second study in mice. Ventricular fibrillation following butane gas inhalation; pp.

Suicide by Inhalation of Suffocative Gas

There were some cerebral remnants in the thalamic regions, and the posterior fossa structures appeared to be preserved. In addition, abuse of other volatile organic solvents cannot be excluded. Metabolism and Disposition 4. Acute Exposure Guideline Levels.

Suicide by Inhalation of Suffocative Gas | The Bulletin of Legal Medicine

It was highly Jose Quero, M. Experiments with dogs Chenoweth ; Krantz et al.

Butane appears to be negative in the Ames test, with and without metabolic activation citation of an unpublished report in Moore The only study with human volunteers Patty and Yant is rather old and focused on the warning properties of butane. It is poorly soluble in water. Concentrations of hydrocarbons in tissues as a measure of toxicity. Carcinogenicity studies and studies on reproductive toxicity are lacking. Because details of the study were lacking and because the tests were conducted in anesthetized dogs, no clear conclusions can be drawn from this study.

Glutethimide Methyprylon Piperidione Pyrithyldione. Nuckolls exposed groups of three guinea pigs to butane at 21, ppm or 50, ppm for 5, 30, 60, or min.

The concentration-response curve appears to be very steep, indicating that a large uncertainty factor is unnecessary. Guinea pigs exposed at 21, ppm showed occasional chewing movements and irregular or rapid breathing, but the effects did not worsen as the exposure duration increased.


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The relationship of hydranencephaly with multicystic encephalomalacia has been stressed repeatedly Lindenberg and SwansonAicardi et al. A year-old boy was found unconsciousness as a result of butane abuse; he died 34 h after the exposure despite resuscitation efforts Rieder-Scharinger et al.

Downloads Download data is not yet available. The portion of left occipital lobe has been spared umer limbs were hvootonic. The infant did not breathe spontaneously; he was resuscitated, intubated, and ventilated artificially, but died 11 h after birth Gosseye et al. Mice and rats were exposed to butane for 2 and 4 h, respectively. Cardiopulmonary resuscitation was commenced.

Prevention How can I tell if my child is using drugs?

A total uncertainty factor of 3 is considered sufficient for toxicokinetic and toxicodynamic differences between individuals and interspecies differences. Severe encephalopathy was observed in a year-old girl as the result of butane abuse.

The chamber concentration was periodically analyzed. Total uncertainty factor of 3 for differences between species and individuals. Thirteen of these cases were associated with butane Bowen et al.

Although the reduction in concentration can be regarded as negligible for short-exposure durations because of general variation in actual exposure concentrations, a mean exposure duration of 1 min is intoxicagion as starting point for time scaling to 8 h of exposure.

Isobutane is primarily used by refineries to enhance increase the octane number of motor gasoline.